What is the background of Celltex Therapeutics Corporation?
Celltex Therapeutics Corporation, a Houston-based biotechnology company dedicated to generating technological breakthroughs in the autologous stem cell field and to improving the quality of life for those suffering from injuries or degenerative disease.
It was formed in 2011 by David G. Eller and Stanley C. Jones to spearhead breakthroughs in regenerative medicine through the use of autologous, adult, adipose-derived, mesenchymal stem cells.
What is Regenerative Medicine?
Regenerative medicine refers to innovative medical technologies that enable the body to repair, replace, restore and regenerate damaged or diseased cells, tissues or organs.
Regenerative medicine works to extend healthy life spans and improve the quality of life by supporting and activating the body’s natural healing. It is one of the most important and promising new areas of the life sciences and has the potential to radically transform our understanding and treatment of disease.
We are constantly undergoing structural renewal by replacing molecular components of our tissues yet the human body loses effective regenerative capacities as we age.
Regenerative medicine involves bringing together stem cell physiology, knowledge of cell growth and death, stimulation of cell replacement and the factors that regulate these and the knowledge of the supporting structures between cells.
What is Cell Therapy?
Cell therapy is the use of stem cells and other regenerative cells to repair, restore, and regenerate, damaged or diseased cells, tissues, or organs.
Cell-based regenerative medicine is not new. Stem cell-based therapies in the form of bone marrow transplants have been used for over 40 years for the treatment of leukemia. Similarly, epithelial stem cell-based treatments have been widely used for many years for burns and corneal disorders.
The scope of potential cell-based therapies has expanded in recent years due to major steps forward in cell research and an increased understanding of the clinical applications of adult stem cells.
What are Stem Cells?
Stem cells are the foundation cells for every organ, tissue and cell in the body. The highly specialized cells that make up these tissues originally came from an initial pool of stem cells formed shortly after fertilization. Stem cells are undifferentiated or “blank” cells that have not yet fully specialized. Stem cells are one part of the tissue repair mechanism found in all mammalian tissue types. When a stem cell divides, each new cell has the potential to either remain a stem cell or differentiate into a specific cell type with a specialized function, such as a bone, cartilage or muscle cell, a red blood cell, or a neuron, based upon the microenvironments. These characteristics distinguish stem cells from other cell types. They also have the capacity to secrete various compounds that can stimulate other cells to regenerate and repair.
There are many different types of stem cells. These include embryonic stem cells that exist only at the earliest stage of embryonic development and can form all cell types of the body. There are various types of “adult” or “tissue specific” stem cells that exist in a number of different adult tissues like bone marrow and adipose (fat) tissue. It is known that different types of stem cells have different potential in regard to the cell types they can become.
What are Mesenchymal Stem Cells?
The two most common types of adult stem cells are Hematopoietic Stem Cells, which form all types of blood cells,and Mesenchymal Stem Cells, which give rise to a variety of other cell types, including bone cells (osteocytes), cartilage cells (chondrocytes), fat cells (adipocytes), and other kinds of connective tissue cells, such as those in tendons.
What is Autologous?
Autologous means obtained from the same individual. Celltex’s procedures use the regenerative cells from the individual’s own adipose (fat) tissue.
What is Allogeneic?
Allogeneic means derived from a different individual of the same species.