What are Mesenchymal Stem Cells?
Celltex is focused on Mesenchymal Stem Cells or MSCs because they are readily found in the body and can give rise to many different cell types. Mesenchymal stem cells can become bone, cartilage, muscle, nerves, fat and pancreatic beta cells, along with other types of cells.
Other than the MSCs ability to become numerous different cell types, they also have the ability to:
- Fight inflammation
- Prevent cell death
- Form new blood vessels
- Direct the immune system, using other repair cell types to aid in healing
Mesenchymal stem cells can be found in practically every tissue of your body. They are most readily taken from bone marrow, umbilical cord blood, placenta and fat. Upon looking for the best possible source for MSCs, we conducted a lot of research into ease of retrieving cells and ensuring high stem cell volumes.
When comparing different sources, we found that fat tissue consistently had high quantities of MSCs. For example, in bone marrow, MSCs constituted just 0.0001%-0.01% of all bone marrow nucleated cells (Pittenger, et al). Fat tissue typically contains 100,000 MSCs in each gram of fat (Sen, et al) and also the differentiation capacity is less affected by one’s age (Jo, et al).